Peter H Krammer Selected Research

Death Domain Receptors

1/2018	Neutralization of CD95 ligand protects the liver against ischemia-reperfusion injury and prevents acute liver failure.
11/2015	Combinatorial treatment of CD95L and gemcitabine in pancreatic cancer cells induces apoptotic and RIP1-mediated necroptotic cell death network.
7/2010	ΔNp73β is oncogenic in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria.
4/2010	Interference with the p53 family network contributes to the gain of oncogenic function of mutant p53 in hepatocellular carcinoma.
10/2009	Parathyroid hormone-related protein confers chemoresistance by blocking apoptosis signaling via death receptors and mitochondria.
3/2009	Inhibition of constitutively activated nuclear factor-kappaB induces reactive oxygen species- and iron-dependent cell death in cutaneous T-cell lymphoma.
2/2008	Construction of optimized bispecific antibodies for selective activation of the death receptor CD95.
7/2006	Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma.
1/2006	Death receptor signaling and its function in the immune system.
7/2005	Transforming growth factor beta can mediate apoptosis via the expression of TRAIL in human hepatoma cells.

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Peter H Krammer Research Topics

Disease

45	Neoplasms (Cancer) 10/2021 - 02/2002
9	Hepatocellular Carcinoma (Hepatoma) 01/2012 - 06/2004
8	Leukemia 01/2018 - 12/2005
7	Lymphoma (Lymphomas) 01/2019 - 06/2004
5	Carcinogenesis 04/2010 - 04/2004
4	Necrosis 01/2018 - 02/2002
4	T-Cell Leukemia (Leukemia, T Cell) 01/2018 - 01/2003
4	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 07/2017 - 03/2009
4	Autoimmune Diseases (Autoimmune Disease) 02/2016 - 02/2002
4	Inflammation (Inflammations) 01/2010 - 09/2002
3	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2017 - 08/2012
3	Carcinoma (Carcinomatosis) 09/2010 - 06/2003
3	Multiple Sclerosis 01/2006 - 02/2002
3	Infections 12/2005 - 02/2002
2	T-Cell Lymphoma (Lymphoma, T Cell) 01/2017 - 03/2009
2	Neoplasm Metastasis (Metastasis) 11/2016 - 08/2016
2	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 01/2016 - 05/2006
2	Thrombocytopenia (Thrombopenia) 01/2016 - 02/2015
2	Pancreatic Neoplasms (Pancreatic Cancer) 11/2015 - 01/2012
2	Hodgkin Disease (Hodgkin's Disease) 10/2013 - 08/2012
2	Nausea 02/2007 - 06/2003
2	Spinal Cord Injuries (Spinal Cord Injury) 05/2006 - 04/2004
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 02/2002 - 02/2002
1	Splenomegaly 12/2019
1	Reperfusion Injury 01/2018
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2018
1	Ischemia 01/2018
1	Liver Failure 01/2018
1	Acute Liver Failure (Fulminant Hepatic Failure) 01/2018
1	Multiple Myeloma 01/2017
1	Lymphoid Leukemia 02/2015
1	Wilms Tumor (Wilm's Tumor) 01/2014
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 10/2013
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 12/2012
1	Rheumatoid Arthritis 12/2012

Drug/Important Bio-Agent (IBA)

14	Death Domain ReceptorsIBA 01/2018 - 02/2002
9	Fas Ligand Protein (Fas Ligand)IBA 01/2018 - 02/2003
9	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2003
8	LigandsIBA 01/2018 - 02/2002
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 06/2004
5	Pharmaceutical PreparationsIBA 10/2021 - 04/2004
5	CaspasesIBA 01/2018 - 02/2002
5	wogoninIBA 01/2018 - 12/2006
5	rocaglamideIBA 01/2017 - 10/2007
4	Interleukin-4 (Interleukin 4)IBA 05/2010 - 09/2002
3	Antineoplastic Agents (Antineoplastics)IBA 08/2012 - 06/2003
3	AntibodiesIBA 10/2010 - 02/2008
3	NF-kappa B (NF-kB)IBA 03/2009 - 01/2003
3	Cisplatin (Platino)FDA LinkGeneric 02/2004 - 02/2002
3	Caspase 8 (Caspase-8)IBA 02/2004 - 02/2003
2	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2019 - 03/2009
2	Histone Deacetylase InhibitorsIBA 01/2019 - 09/2010
2	CytokinesIBA 01/2018 - 01/2010
2	Therapeutic UsesIBA 01/2018 - 07/2006
2	Indicators and Reagents (Reagents)IBA 02/2016 - 02/2008
2	navitoclaxIBA 01/2016 - 02/2015
2	FlavonesIBA 02/2015 - 01/2012
2	ApigeninIBA 02/2015 - 01/2012
2	Apoptosis Regulatory ProteinsIBA 02/2015 - 11/2005
2	chrysinIBA 02/2015 - 01/2012
2	Messenger RNA (mRNA)IBA 01/2014 - 12/2009
2	AnnexinsIBA 01/2013 - 10/2010
2	Glutathione (Reduced Glutathione)IBA 03/2009 - 02/2002
2	Transforming Growth Factor beta (TGF-beta)IBA 07/2008 - 07/2005
2	Cycloheximide (Cicloheximide)IBA 02/2008 - 12/2006
2	GlucocorticoidsIBA 02/2007 - 06/2003
2	Protein Isoforms (Isoforms)IBA 12/2006 - 02/2003
1	Deoxyglucose (2 Deoxy D glucose)IBA 10/2021
1	Glucose (Dextrose)FDA LinkGeneric 10/2021
1	Syk KinaseIBA 12/2019
1	dectin 1IBA 12/2019
1	NADP (NADPH)IBA 12/2019
1	AutoantibodiesIBA 12/2019
1	IgA receptor (protein B)IBA 01/2019
1	EnzymesIBA 01/2018
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2018
1	FlavonoidsIBA 01/2018
1	Sorafenib (BAY 43-9006)FDA Link 07/2017
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2017
1	Dimethyl FumarateIBA 11/2016
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 08/2016
1	PhytochemicalsIBA 08/2016
1	Monoclonal AntibodiesIBA 02/2016
1	antineoplaston A10 (A 10)IBA 01/2016
1	DiterpenesIBA 12/2015
1	Gemcitabine FDA Link 11/2015
1	baicaleinIBA 02/2015
1	venetoclaxIBA 02/2015
1	LuteolinIBA 02/2015
1	WT1 ProteinsIBA 01/2014
1	Interleukin-13IBA 10/2013
1	InterferonsIBA 10/2013
1	Estradiol (Delestrogen)FDA LinkGeneric 12/2012
1	Antimitotic AgentsIBA 12/2012
1	2-MethoxyestradiolIBA 12/2012

Therapy/Procedure

22	Therapeutics 10/2021 - 04/2002
14	Drug Therapy (Chemotherapy) 08/2016 - 02/2002
3	Ligation 04/2010 - 04/2004
2	Transplantation 01/2018 - 01/2018
1	Treatment Delay 11/2016